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APIs and Intermediates
Fumagillin CAS 23110-15-8

Fumagillin CAS 23110-15-8

CAS NO: 23110-15-8
Molecular Formula: C26H34O7
Molecular Weight: 458.54400
EINECS NO: 245-433-8
MDL NO: MFCD03990453

Відомості про продукт

Product Description:

Product Name: Fumagillin CAS NO: 23110-15-8

 

Synonyms:

fumidil;

h-3;

mono5-methoxy-4-2-methyl-3-(3-methyl-2-butenyl)oxiranyl-1-oxaspiro2.5octan-6-ylester;

 

Chemical Physical Properties:

Appearance: Light yellow solid

Assay : Greater than or equal to 99.0 percent

Density: 1.19g/cm3

Boiling Point: 608.8 degree at 760mmHg

Melting Point: >190 degree -192 degree

Flash Point: 198.8 degree

Refractive Index: 1.562

Storage Condition: -20 degree

Vapor Pressure: 2.7E-16mmHg at 25 degree

Sensitive: Air Sensitive

 

Safety Information:

Safety Statement: S36

Risk Statement: R22

Hazard Code: Xn

 

Fumagillin is a complex biomolecule and used as an antimicrobial agent. It was isolated in 1949 from the microbial organism Aspergillus fumigatus. Fumagillin is a polyene mycotoxin isolated from Aspergillus fumigatus in 1951 as a potent antiprotozoan for the treatment of amoebiasis. More recently, fumagillin has been shown to inhibit endothelial cell proliferation and angiogenesis by inhibiting methionine aminopeptidase-2 (MetAP-2).

 

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