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CAS NO: 23110-15-8
Molecular Formula: C26H34O7
Molecular Weight: 458.54400
EINECS NO: 245-433-8
MDL NO: MFCD03990453
Product Description:
Product Name: Fumagillin CAS NO: 23110-15-8
Synonyms:
fumidil;
h-3;
mono5-methoxy-4-2-methyl-3-(3-methyl-2-butenyl)oxiranyl-1-oxaspiro2.5octan-6-ylester;
Chemical Physical Properties:
Appearance: Light yellow solid
Assay : Greater than or equal to 99.0 percent
Density: 1.19g/cm3
Boiling Point: 608.8 degree at 760mmHg
Melting Point: >190 degree -192 degree
Flash Point: 198.8 degree
Refractive Index: 1.562
Storage Condition: -20 degree
Vapor Pressure: 2.7E-16mmHg at 25 degree
Sensitive: Air Sensitive
Safety Information:
Safety Statement: S36
Risk Statement: R22
Hazard Code: Xn
Fumagillin is a complex biomolecule and used as an antimicrobial agent. It was isolated in 1949 from the microbial organism Aspergillus fumigatus. Fumagillin is a polyene mycotoxin isolated from Aspergillus fumigatus in 1951 as a potent antiprotozoan for the treatment of amoebiasis. More recently, fumagillin has been shown to inhibit endothelial cell proliferation and angiogenesis by inhibiting methionine aminopeptidase-2 (MetAP-2).
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